PROFILE

안준용 교수

Brain organoid-based virtual cell modeling predicts novel autism and neurodevelopmental disorder genes

Brain organoid-based virtual cell modeling combines single-cell transcriptomics with AI-driven methodologies to predict novel genes associated with autism and neurodevelopmental disorders.
Utilizing the comprehensive Neural Organoid Cell Atlas with Perturbation, this approach uncovers critical genes that conventional genomic analyses typically miss.

고려대학교 바이오시스템의과학부

CAREER

2022-현재 부교수, 고려대학교
2019-2022 조교수, 고려대학교
2015-2019 박사 후 연구원, 캘리포니아 대학 (샌프란시스코, UCSF)

EDUCATION

2012-2016 박사 (신경생물학), 퀸즐랜드 대학교, 호주
2010-2011 석사 (분자생물학), 퀸즐랜드 대학교, 호주
2005-2010 학사 (분자생물학), 건국대학교, 대한민국

PUBLICATIONS

1. Kim SW*, Lee H*, Song DY, Lee GH, Ji J, Park JW, Han JH, Lee JW, Byun HJ, Son JH, Kim YR, Lee
Y, Kim J, Jung A, Lee JH, Kim EH, Kim SH, Lee JH, Satterstrom FK, Girirajan S, Børglum AD, Grove
J, Kim EJ**, Werling DM**, Yoo HJ**, An JY**, Whole genome sequencing analysis identifies sex
differences of familial pattern contributing to phenotypic diversity in autism. Genome Medicine, 2024
2. Kim JH*, Koh IG, Lee H, Lee GH, Song DY, Kim SW, Kim Y, Han JH, Bong G, Lee J, Byun H, Son JH,
Kim YR, Lee Y, Kim JJ, Park JW, Kim IB, Choi JK, Jang JH, Trost B, Lee J, Kim E, Yoo HJ**, An JY**,
Short tandem repeat expansions in cortical layer-specific genes implicate in phenotypic severity and
adaptability of autism spectrum disorder, Psychiatry and Clinical Neurosciences, 2024
3. Song KJ*, Choi S*, Kim K*, Hwang HS*, Chang E, Park JS, Shim SB, Choi S, Heo YJ, An WJ, Yang
DY, Cho KC, Ji W, Choi CM, Lee JC, Kim HR, Yoo J, Ahn HS, Lee GH, Hwa C, Kim S, Kim KG, Kim
MS, Paek E, Na S**, Jang SJ**, An JY**, Kim KP**, Proteogenomic Analysis of a Korean Cohort
Reveals Lung Cancer Subtypes Predictive of Metastasis, Chromosome Instability, and Tumor
Microenvironment, Nature Communications, 2024
4. Kim Y*, Jeong M*, Koh IG, Kim C, Lee H, Kim JH, Yurko R, Kim IB, Park J, Werling DM, Sanders SJ,
An JY**, CWAS-Plus: Estimating category-wide association of rare noncoding variation from wholegenome
sequencing data with cell-type-specific functional data, Briefings in Bioinformatics, 2024
5. Darbandi SF*, An JY*, Lim K, Page NF, Liang L, Young DM, Ypsilanti AR, State MW, Nord AS, Sanders
SJ**, Rubenstein JLR**, Five autism-associated transcriptional regulators target shared loci proximal
to brain-expressed genes, Cell Reports, 2024