PROFILE

우태균 팀장

Inhibition of SOD1 trimerization is a novel drug target for ALS disease

Oral administration of Amisodin in ALS mouse model protected against neuronal loss, and extended the lifespan of ALS mice by up to 3 weeks. The findings indicate that amisodin, which targets trimeric SOD1, may be a strong therapeutic candidate for both familial and sporadic ALS

PRG S&Tech 연구본부

EDUCATION

2006. 03. ~ 2012. 08.
B.S., Department of Molecular Biology, Pusan National University.
2012. 09. ~ 2018. 02.
Ph.D., Department of Integrated Biological Science, Pusan National University.
2018. 02. ~ present
Principal Researcher, PRG S&T Research Institute

Publications

1. Woo TG, Han J, Kim Y, Hwang YJ, Lee M, Kang SM, Park S, Ji Y, Chung YH, Baek S, Shin E, Kim M, Jang H, Shin YJ, Kwon Y, Kim BH, Park BJ. (2025) Inhibition of SOD1 trimerization is a novel drug target for ALS disease. Transl Neurodegener. 12;14(1):21
2. Chung YH, Park S, Lee M, Lee J, Ji Y, Song YJ, Woo TG, Shin E, Baek S, Hwang YJ, Kim Y, Kim M, Han J, Kim HR, Choi J, Kim BH, Park BJ. (2024) Therapeutic effect of novel drug candidate, PRG-N-01, on NF2 syndrome-related tumor. Neuro Oncol. noae282. Online ahead of print
3. Park S, Oh AY, Hong BS, Shin YJ, Jang H, Seo H, Kang SM, Woo TG, Park HP, Jeong J, Kim HJ, Kim BH, Kwon Y, Park BJ. (2024) The therapeutic effect of DX2 inhibition in nicotine-induced lung cancer progression. 10;32(4):200875
4. Kim BH, Chung YH, Woo TG, Kang SM, Park S, Kim M, Park BJ. (2024) NF2-Related Schwannomatosis (NF2): Molecular Insights and Therapeutic Avenues. Int J Mol Sci. 25(12):6558
5. Kim BH, Chung YH, Woo TG, Kang SM, Park S, Park BJ. (2023) Progerin, an Aberrant Spliced Form of Lamin A, Is a Potential Therapeutic Target for HGPS. Cells. 18;12(18):2299